SCHEMBL446484

SCHEMBL446484

O=C/C=C/c1ccccc1[N+](=O)[O-]

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 1/20 0.65
MAPT P10636 11/20 0.59
MAOB P27338 1/20 0.54
ALDH1A1 P00352 7/20 0.54
RAB9A P51151 6/20 0.54
NPC1 O15118 4/20 0.54
MAPK1 P28482 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
TDP1 Q9NUW8 3/20 0.54
KMT2A Q03164 6/20 0.51
MEN1 O00255 5/20 0.51
KDM4E B2RXH2 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
NFKB1 P19838 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
CDK4 P11802 1/20 0.50
CCND1 P24385 1/20 0.50
CYP19A1 P11511 1/20 0.50
HTT P42858 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566396 1.00 SOS1 (0.65) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL29414981 1.00 SOS1 (0.65) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL5440780 0.90 SOS1 (0.71) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL5440784 0.90 SOS1 (0.71) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL11049170 0.86 MAPT (0.69) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL14935499 0.86 MAPT (0.69) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL9978289 0.86 MAPT (0.69) SOS1MAPTMAOBALDH1A1RAB9A
Formaldehyde SCHEMBL27619255 0.85 ALDH1A1 (0.61) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL3846862 0.85 SOS1 (0.65) SOS1MAPTMAOBALDH1A1RAB9A
SCHEMBL3846864 0.85 SOS1 (0.65) SOS1MAPTMAOBALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 934 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630758-B2 Downhole methods and compositions used in such DORF KETAL CHEMICALS FZE (AE) 2026-05-19 US claimed
US-12497557-B2 Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore DORF KETAL CHEMICALS FZE (AE) 2025-12-16 US claimed
US-12241021-B2 Method for fracking of simulation of hydrocarbon bearing formation DORF KETAL CHEMICALS FZE (AE) 2025-03-04 US claimed
US-20250011644-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2025-01-09 US claimed
US-20240301277-A1 Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore DORF KETAL CHEMICALS FZE (AE) 2024-09-12 US claimed
US-20240279533-A1 DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2024-08-22 US claimed
US-20240254383-A1 NOVEL DOWNHOLE METHODS AND COMPOSITIONS USED IN SUCH DORF KETAL CHEMICALS FZE (AE) 2024-08-01 US claimed
US-12018210-B2 Methods for stimulating a hydrocarbon-bearing formation by perforating a wellbore and introducing an acidic composition in the wellbore DORF KETAL CHEMICALS FZE (AE) 2024-06-25 US claimed
US-20240191128-A1 Methods for Stimulating a Hydrocarbon-bearing Formation by Perforating a Wellbore and Introducing an Acidic Composition in the Wellbore DORF KETAL CHEMICALS FZE (AE) 2024-06-13 US claimed
US-11865086-B2 Cinnamaldehyde derivative compounds and methods of use for cinnamaldehyde derivative compounds nicotine cessation PACIFIC UNIVERSITY (US) 2024-01-09 US claimed
EP-0240659-B2 N-substituted 3,4,5,6-tetrahydrophthalimides and their precursors BASF AG (DE) 1994-10-26 EP claimed
US-5296275-A Water soluble nonionic resin carrier, a light sensitive compound which colors in response to protons, wetting agents, thickeners and flow aids XYTRONYX, INC. (US) 1994-03-22 US claimed
WO-1994001503-A1 PHOTOTRANSCHROMIC INK XYTRONYX, INC. (US) 1994-01-20 WO claimed
US-5270370-A Contacting with trans-cinnamaldehyde ALBRIGHT & WILSON LIMITED (GB) 1993-12-14 US claimed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 EP claimed
EP-0290750-A2 Systems for the visualization of exposure to ultraviolet radiation and for the utilization of ultraviolet radiation to effect color changes XYTRONYX, INC. (US) 1988-11-17 EP claimed
WO-1988007222-A1 SYSTEMS FOR THE VISUALIZATION OF EXPOSURE TO ULTRAVIOLET RADIATION AND FOR THE UTILIZATION OF ULTRAVIOLET RADIATION TO EFFECT COLOR CHANGES XYTRONYX, INC. (US) 1988-09-22 WO claimed
EP-0240659-A2 N-substituted 3,4,5,6-tetrahydrophthalimides and their precursors BASF Aktiengesellschaft (DE) 1987-10-14 EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630758-B2 Downhole methods and compositions used in such IL1B, GET3, IL17A SOS1 286/4885MAPT 4649/4885MAOB 3222/4885
US-11865086-B2 Cinnamaldehyde derivative compounds and methods of use for cinnamaldehyde derivative compounds nicotine cessation CES2, NNT, NNMT SOS1 3502/4885MAPT 1521/4885MAOB 63/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.