Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726340 | 1.00 | PPARG (0.51) | PPARGPPARAPPARDTSHRTP53 | |
| SCHEMBL4729736 | 0.86 | SMN1; SMN2 (0.41) | PPARGPPARAPPARDTSHRTP53 | |
| SCHEMBL4729739 | 0.86 | SMN1; SMN2 (0.41) | PPARGPPARAPPARDTSHRTP53 | |
| SCHEMBL4727006 | 0.81 | MCL1 (0.43) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4727000 | 0.81 | MCL1 (0.43) | PPARGPPARAPPARDTSHRHSD17B10 | |
| SCHEMBL4727010 | 0.79 | MCL1 (0.44) | PPARGPPARAPPARDTSHRTP53 | |
| SCHEMBL4726569 | 0.72 | PPARD (0.76) | PPARGPPARAPPARDPTGDR2 | |
| SCHEMBL4726571 | 0.72 | PPARD (0.76) | PPARGPPARAPPARDPTGDR2 | |
| SCHEMBL4729074 | 0.69 | HTT (0.40) | PPARGPPARAPPARDTSHRTP53 | |
| SCHEMBL4729069 | 0.69 | HTT (0.40) | PPARGPPARAPPARDTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |