Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727000 | 0.92 | MCL1 (0.43) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4727006 | 0.92 | MCL1 (0.43) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4729531 | 0.84 | MAPT (0.43) | MCL1PPARGPPARAPPARDHSD17B10 | |
| SCHEMBL4726337 | 0.79 | PPARG (0.51) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4726340 | 0.79 | PPARG (0.51) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4726366 | 0.77 | HSD17B10 (0.39) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4726370 | 0.77 | HSD17B10 (0.39) | MCL1PPARGPPARAPPARDHTT | |
| SCHEMBL4729526 | 0.76 | PLA2G2A (0.43) | MCL1PPARGPPARAPPARD | |
| SCHEMBL4729524 | 0.76 | PLA2G2A (0.43) | MCL1PPARGPPARAPPARD | |
| SCHEMBL4725597 | 0.74 | PPARD (0.45) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |