Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.46 |
| ▸ | PPARA | Q07869 | 8/20 | 0.46 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726354 | 1.00 | PPARG (0.46) | PPARGPPARAPPARDSMN1; SMN2CYP19A1 | |
| SCHEMBL4729792 | 0.84 | SMN1; SMN2 (0.43) | PPARGPPARAPPARDSMN1; SMN2MAPT | |
| SCHEMBL4728537 | 0.84 | SMN1; SMN2 (0.43) | PPARGPPARAPPARDSMN1; SMN2MAPT | |
| SCHEMBL4784313 | 0.83 | PPARG (0.66) | PPARGPPARAPPARDMAPT | |
| SCHEMBL4784306 | 0.83 | PPARG (0.66) | PPARGPPARAPPARDMAPT | |
| SCHEMBL4730360 | 0.83 | PPARG (0.66) | PPARGPPARAPPARDMAPT | |
| SCHEMBL4728889 | 0.83 | PPARG (0.66) | PPARGPPARAPPARDMAPT | |
| SCHEMBL4729096 | 0.79 | PPARD (0.73) | PPARGPPARAPPARDNR1H4 | |
| SCHEMBL4729706 | 0.77 | PPARG (0.45) | PPARGPPARAPPARDSMN1; SMN2PTPN1 | |
| SCHEMBL4727917 | 0.72 | PLA2G4B (0.53) | PPARGPPARAPPARDSMN1; SMN2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |