SCHEMBL4728889

SCHEMBL4728889

CC/C(=N/OCc1nc(-c2ccc(C)cc2)oc1C)c1ccc(OCC(=O)O)cc1

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.66
PPARA Q07869 9/20 0.66
PPARD Q03181 3/20 0.66
TP53 P04637 3/20 0.49
POLB P06746 2/20 0.49
MAPT P10636 3/20 0.48
FFAR1 O14842 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730360 1.00 PPARG (0.66) PPARGPPARAPPARDTP53POLB
SCHEMBL4784306 0.93 PPARG (0.66) PPARGPPARAPPARDTP53MAPT
SCHEMBL4784313 0.93 PPARG (0.66) PPARGPPARAPPARDTP53MAPT
SCHEMBL4728605 0.84 PPARG (0.52) PPARGPPARAPPARDTP53POLB
SCHEMBL4728895 0.83 PPARG (0.61) PPARGPPARAPPARDPOLBFFAR1
SCHEMBL4726354 0.83 PPARG (0.46) PPARGPPARAPPARDMAPT
SCHEMBL4726360 0.83 PPARG (0.46) PPARGPPARAPPARDMAPT
SCHEMBL4782933 0.82 PPARG (0.78) PPARGPPARAPPARDTP53POLB
SCHEMBL4727541 0.82 PPARG (0.78) PPARGPPARAPPARDTP53POLB
SCHEMBL15543185 0.80 PPARG (0.55) PPARGPPARAPPARDTP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed