Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816804 | 0.98 | NPSR1 (0.47) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL2141041 | 0.93 | NPSR1 (0.42) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL668965 | 0.89 | NPSR1 (0.40) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL9806699 | 0.86 | NPSR1 (0.52) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL4870814 | 0.86 | NPSR1 (0.52) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL594374 | 0.86 | NPSR1 (0.52) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL759802 | 0.84 | NPSR1 (0.54) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL11378256 | 0.83 | NPSR1 (0.42) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| Ethylene SCHEMBL11214910 | 0.82 | NPSR1 (0.48) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 | |
| SCHEMBL9806701 | 0.80 | NPSR1 (0.47) | NPSR1ALDH1A1L3MBTL1MAPTCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166734-A | Novel aminopyridine compounds having Syk inhibitory activity | JAPAN TOBACCO INC (JP) | 2008-04-23 | — | — | CN | disclosed |
| WO-2008011130-A2 | AMIDE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-24 | — | — | WO | disclosed |