Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 1/20 | 0.78 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | CDC7 | O00311 | 4/20 | 0.57 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.57 |
| ▸ | GSK3B | P49841 | 7/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | KDM4B | O94953 | 1/20 | 0.45 |
| ▸ | KDM5C | P41229 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936506 | 0.88 | RAB9A (1.00) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4207689 | 0.85 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4208111 | 0.85 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4213116 | 0.85 | PDPK1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL17268781 | 0.85 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4207684 | 0.85 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL5641135 | 0.84 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL15703311 | 0.81 | NPC1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4209817 | 0.81 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 | |
| SCHEMBL4208313 | 0.81 | RAB9A (0.77) | RAB9ANPC1SMN1; SMN2MAPTPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002575-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-03 | — | — | WO | disclosed |