Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.66 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836198 | 0.88 | NR1H4 (0.54) | S1PR1PPARGPPARARXRARXRB | |
| SCHEMBL4836204 | 0.88 | NR1H4 (0.54) | S1PR1PPARGPPARARXRARXRB | |
| SCHEMBL3419327 | 0.87 | S1PR1 (0.63) | S1PR1PPARGPPARARXRARXRB | |
| SCHEMBL3419326 | 0.87 | S1PR1 (0.63) | S1PR1PPARGPPARARXRARXRB | |
| SCHEMBL16914904 | 0.85 | S1PR1 (0.61) | S1PR1PPARGPPARAMAOBPPARD | |
| SCHEMBL17601795 | 0.85 | S1PR1 (0.61) | S1PR1PPARGPPARAMAOBPPARD | |
| SCHEMBL17601803 | 0.85 | S1PR1 (0.60) | S1PR1PPARGPPARAMAOBNPC1 | |
| SCHEMBL17601801 | 0.85 | S1PR1 (0.60) | S1PR1PPARGPPARAMAOBNPC1 | |
| SCHEMBL16269783 | 0.81 | MAOB (0.60) | S1PR1PPARGPPARAMAOBPPARD | |
| SCHEMBL16269498 | 0.81 | MAOB (0.60) | S1PR1PPARGPPARAMAOBPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2008035359-A2 | OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |