Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4581221 | 0.84 | HSP90AA1 (0.56) | HSP90AA1 | |
| SCHEMBL20117828 | 0.82 | HSP90AA1 (0.54) | HSP90AA1 | |
| SCHEMBL4726191 | 0.82 | MMP9 (0.38) | HSP90AA1 | |
| SCHEMBL4779386 | 0.80 | HSP90AA1 (0.53) | HSP90AA1 | |
| SCHEMBL4579921 | 0.80 | HSP90AA1 (0.56) | HSP90AA1 | |
| SCHEMBL20117824 | 0.79 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL20117830 | 0.79 | HSP90AA1 (0.51) | HSP90AA1 | |
| SCHEMBL4581684 | 0.77 | HSP90AA1 (0.53) | HSP90AA1 | |
| SCHEMBL4579731 | 0.77 | HSP90AA1 (0.61) | HSP90AA1 | |
| SCHEMBL4579386 | 0.77 | HSP90AA1 (0.53) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024978-A2 | TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | claimed |
| WO-2008024978-A2 | TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |