Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28267718 | 0.83 | KMT2A (0.49) | KMT2AMEN1RORCNPY5RPOLB | |
| SCHEMBL16099079 | 0.80 | KDM4E (0.50) | KMT2ARORCNPY5RPOLBMAPT | |
| SCHEMBL6351807 | 0.80 | POLB (0.67) | KMT2ARORCNPY5RPOLBMAPT | |
| SCHEMBL24667919 | 0.80 | KMT2A (0.51) | KMT2AMEN1RORCNPY5RPOLB | |
| SCHEMBL4728764 | 0.78 | MEN1 (0.56) | KMT2AMEN1RORCNPY5RPOLB | |
| SCHEMBL28266267 | 0.78 | NPY5R (0.59) | KMT2AMEN1RORCNPY5RMAPT | |
| SCHEMBL16093698 | 0.78 | ALDH1A1 (0.58) | KMT2AMEN1RORCPOLBMAPT | |
| SCHEMBL29780042 | 0.76 | BCHE (0.59) | KMT2AMEN1NPY5RPOLBMAPT | |
| SCHEMBL150044 | 0.76 | BCHE (0.59) | KMT2AMEN1NPY5RPOLBMAPT | |
| SCHEMBL26237871 | 0.75 | MEN1 (0.59) | KMT2AMEN1RORCNPY5RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |