SCHEMBL4726907

SCHEMBL4726907

[CH2]C(O)Cc1cccnc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.56
KDM4E B2RXH2 1/20 0.50
NAPRT Q6XQN6 1/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2D6 P10635 1/20 0.48
CHRNA7 P36544 1/20 0.47
ALDH1A1 P00352 1/20 0.46
CHRNB2 P17787 3/20 0.46
CHRNA4 P43681 3/20 0.46
CYP2A6 P11509 1/20 0.44
TBXAS1 P24557 1/20 0.44
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
RECQL P46063 1/20 0.43
CYP2C19 P33261 1/20 0.43
HIF1A Q16665 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547411 0.83 FDPS (0.59) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL27492973 0.81 CHRNA7 (0.58) FDPSKDM4ENAPRTCHRNA7CYP2A6
SCHEMBL2096123 0.80 FDPS (0.51) FDPSNAPRTCYP1A2CYP2D6CHRNA7
SCHEMBL14828666 0.80 FDPS (0.56) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL3835687 0.80 FDPS (0.56) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL12632304 0.80 FDPS (0.56) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL30082869 0.80 FDPS (0.56) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL9257518 0.78 FDPS (0.54) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL11798962 0.77 SMN1; SMN2 (0.56) FDPSKDM4ENAPRTCYP1A2CYP2D6
SCHEMBL21947449 0.77 FDPS (0.53) FDPSKDM4ENAPRTCYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103508930-B Two (aminodithioformic acid)-1,3-propylene diester compounds and synthetic method, pharmaceutical composition and purposes PEKING UNIVERSITY (CN) 2016-01-27 CN claimed
CN-103508930-A Bis(aminodithioformate)-1,3-propane diester compound, and synthesis method, pharmaceutical composition and use thereof UNIV BEIJING 2014-01-15 CN claimed
CN-103508930-B Two (aminodithioformic acid)-1,3-propylene diester compounds and synthetic method, pharmaceutical composition and purposes PEKING UNIVERSITY (CN) 2016-01-27 CN disclosed
CN-103508930-A Bis(aminodithioformate)-1,3-propane diester compound, and synthesis method, pharmaceutical composition and use thereof UNIV BEIJING 2014-01-15 CN disclosed
WO-2008012546-A2 AZAPEPTIDES FOR USE IN THERAPY AGAINST INTERSTITIAL CYSTITIS SOSEI CO. LTD. (JP) 2008-01-31 WO disclosed