Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783058 | 0.78 | SRC (0.44) | ALDH1A1PTK2 | |
| SCHEMBL4582739 | 0.76 | MAPK9 (0.51) | MAPK10MAPK9ALDH1A1MEN1KMT2A | |
| SCHEMBL4580701 | 0.75 | SYK (0.52) | MAPK10MAPK9MEN1KMT2ACSF1R | |
| SCHEMBL4581557 | 0.72 | SYK (0.50) | MAPK9ALDH1A1MEN1KMT2ACSF1R | |
| SCHEMBL13450261 | 0.68 | MAPK9 (0.57) | MAPK10MAPK9MEN1KMT2AMAPK1 | |
| SCHEMBL4523815 | 0.67 | MAPK9 (0.76) | MAPK10MAPK9MEN1KMT2AMAPK1 | |
| SCHEMBL6154777 | 0.67 | MAPK9 (0.59) | MAPK10MAPK9MEN1KMT2ALMNA | |
| SCHEMBL4580452 | 0.67 | MAPK9 (0.45) | MAPK10MAPK9ALDH1A1MEN1KMT2A | |
| SCHEMBL4580323 | 0.67 | MAPK9 (0.45) | MAPK10MAPK9ALDH1A1MEN1KMT2A | |
| SCHEMBL4582836 | 0.67 | MAPK9 (0.48) | MAPK10MAPK9HSP90AA1HSP90AB1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024963-A1 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | claimed |
| WO-2008024963-A1 | BENZENE, PYRIDINE, AND PYRIDAZINE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |