Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 11/20 | 0.77 |
| ▸ | FYN | P06241 | 9/20 | 0.77 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053252 | 0.88 | FYN (0.79) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL16216051 | 0.87 | PIM1 (0.77) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL1052926 | 0.87 | FYN (1.00) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL1053040 | 0.87 | PIM1 (0.77) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL1051232 | 0.87 | PIM1 (0.77) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL102689 | 0.87 | PIM1 (1.00) | PIM1FYNKCNH2 | |
| SCHEMBL4779099 | 0.87 | FYN (0.79) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL2948048 | 0.87 | FYN (1.00) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL1055979 | 0.87 | FYN (0.80) | PIM1FYNMKNK1KCNH2 | |
| SCHEMBL2951683 | 0.85 | FYN (0.74) | PIM1FYNMKNK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |