Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 9/20 | 0.79 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.77 |
| ▸ | PIM1 | P11309 | 8/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1055016 | 0.89 | FYN (0.81) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1051264 | 0.88 | FYN (0.79) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1052981 | 0.88 | FYN (1.00) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1055876 | 0.88 | FYN (0.79) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1052943 | 0.88 | FYN (0.79) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1055979 | 0.88 | FYN (0.80) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1049305 | 0.88 | FYN (0.74) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL3027305 | 0.87 | FYN (1.00) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL4727112 | 0.87 | PIM1 (0.77) | FYNMKNK1PIM1KCNH2 | |
| SCHEMBL1054758 | 0.86 | FYN (0.76) | FYNMKNK1PIM1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | claimed |
| WO-2008025822-A1 | DIAZOLODIAZINE DERIVATIVES AS KINASE INHIBITORS | CELLZOME LIMITED (GB) | 2008-03-06 | — | — | WO | disclosed |