Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 15/20 | 0.73 |
| ▸ | MEN1 | O00255 | 12/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.73 |
| ▸ | LMNA | P02545 | 7/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 5/20 | 0.73 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.66 |
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4725807 | 0.88 | MAPT (0.72) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL7722872 | 0.88 | MAPT (0.75) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL28445560 | 0.84 | MAPT (0.70) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL19757536 | 0.83 | MAPT (0.68) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL6226561 | 0.82 | MAPT (0.74) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL330445 | 0.82 | MAPT (0.67) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL28906026 | 0.82 | MAPT (0.70) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL30138765 | 0.82 | MAPT (0.70) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL4725265 | 0.81 | NPY5R (0.72) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL6650411 | 0.81 | MAPT (0.72) | MAPTMEN1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |