Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4701132 | 0.81 | KDM5A (0.59) | KDM5AKDM5BMAPTKDM4EALDH1A1 | |
| SCHEMBL5309082 | 0.80 | KDM5A (0.58) | KDM5AKDM5BCSF1R | |
| SCHEMBL1058188 | 0.79 | KDM5A (0.68) | KDM5AKDM5BKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5330015 | 0.78 | KDM5A (0.64) | KDM5AKDM5BKDM4EALDH1A1 | |
| SCHEMBL4647482 | 0.78 | KDM5A (0.64) | KDM5AKDM5BKDM4E | |
| SCHEMBL8142770 | 0.77 | KDM5A (0.62) | KDM5AKDM5B | |
| SCHEMBL10334091 | 0.75 | EGFR (0.68) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10334092 | 0.75 | EGFR (0.68) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5334737 | 0.73 | KDM5A (0.58) | KDM5AKDM5BMAPTKDM4EMEN1 | |
| SCHEMBL18584559 | 0.73 | KDM5A (0.57) | KDM5AKDM5BKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011337-A1 | HCV INHIBITORS | ABBOTT LABORATORIES (US) | 2008-01-24 | — | — | WO | disclosed |