Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.58 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.54 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829907 | 0.92 | GABRA1 (0.53) | KDM5AKDM5BGABRA1GABRB1GABRA3 | |
| SCHEMBL18584559 | 0.90 | KDM5A (0.57) | KDM5AKDM5B | |
| SCHEMBL4647482 | 0.89 | KDM5A (0.64) | KDM5AKDM5B | |
| SCHEMBL5308554 | 0.88 | KDM5A (0.55) | KDM5AKDM5B | |
| SCHEMBL4701132 | 0.85 | KDM5A (0.59) | KDM5AKDM5BCSF1R | |
| SCHEMBL1058188 | 0.82 | KDM5A (0.68) | KDM5AKDM5B | |
| SCHEMBL4297249 | 0.82 | KDM5A (0.54) | KDM5AKDM5BGABRA1GABRB1GABRA3 | |
| SCHEMBL5330015 | 0.82 | KDM5A (0.64) | KDM5AKDM5B | |
| SCHEMBL8142770 | 0.81 | KDM5A (0.62) | KDM5AKDM5B | |
| SCHEMBL4727166 | 0.80 | KDM5A (0.54) | KDM5AKDM5BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017040459-A1 | IMPROVED SOLUBILITY FOR TARGET COMPOUNDS | Aunova Medchem LLC (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |