Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | AHR | P35869 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14544616 | 0.94 | THRB (0.65) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11546092 | 0.93 | SMN1; SMN2 (0.68) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9769453 | 0.92 | THRB (0.67) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3169131 | 0.91 | KMT2A (0.64) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1545948 | 0.89 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2000945 | 0.89 | KMT2A (0.63) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4314263 | 0.89 | SMN1; SMN2 (0.63) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL9969534 | 0.89 | SMN1; SMN2 (0.63) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13528229 | 0.88 | MAPT (0.66) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1996620 | 0.88 | SMN1; SMN2 (0.62) | KMT2AMEN1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | claimed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |