Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727281 | 1.00 | TSHR (0.43) | TSHRESR2LMNASMN1; SMN2NR1I2 | |
| SCHEMBL5824243 | 0.93 | TSHR (0.39) | TSHRESR2 | |
| SCHEMBL5824248 | 0.93 | TSHR (0.39) | TSHRESR2 | |
| SCHEMBL30883078 | 0.84 | — | — | |
| SCHEMBL27610339 | 0.73 | HDAC4 (0.39) | SMN1; SMN2 | |
| SCHEMBL1381818 | 0.73 | — | — | |
| SCHEMBL261715 | 0.73 | — | — | |
| SCHEMBL8025223 | 0.72 | — | — | |
| SCHEMBL8989796 | 0.72 | — | — | |
| SCHEMBL6055452 | 0.71 | HDAC4 (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027162-A2 | 129XE BIOSENSORS AND THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008027162-A2 | 129XE BIOSENSORS AND THEIR USE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-03-06 | — | — | WO | disclosed |