SCHEMBL5824243

SCHEMBL5824243

O/C1=C/CCC(O)CCC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
ESR2 Q92731 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5824248 1.00 TSHR (0.39) TSHRESR2
SCHEMBL4727285 0.93 TSHR (0.43) TSHRESR2
SCHEMBL4727281 0.93 TSHR (0.43) TSHRESR2
SCHEMBL30883078 0.86
SCHEMBL3672165 0.76 TSHR (0.38) TSHR
SCHEMBL3672167 0.76 TSHR (0.38) TSHR
SCHEMBL8025223 0.73
SCHEMBL8989796 0.73
SCHEMBL157595 0.72
SCHEMBL1645488 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060128575-A1 Traction fluid composition GEIGER RENE 2006-06-15 US claimed
WO-2004061057-A1 TRACTION FLUID COMPOSITION DOW GLOBAL TECHNOLOGIES INC. (US) 2004-07-22 WO claimed
US-5504242-A Acyl carbamate containing a hydroxyl group and process for producing the same NIPPON PAINT CO., LTD. (JP) 1996-04-02 US claimed
US-20060128575-A1 Traction fluid composition GEIGER RENE 2006-06-15 US disclosed
WO-2004061057-A1 TRACTION FLUID COMPOSITION DOW GLOBAL TECHNOLOGIES INC. (US) 2004-07-22 WO disclosed
US-6211228-B1 COMPOUNDS WITH AMINO, GUANIDINO AND AMIDINO HETEROCYCLIC COMPOUNDS AXYS PHARMACEUTICALS, INC 2001-04-03 US disclosed
US-6022969-A Compositions and methods for treating mast-cell mediated conditions AXYS PHARMACEUTICALS, INC. (US) 2000-02-08 US disclosed
EP-0782571-A1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION ARRIS PHARMACEUTICAL CORPORATION (US) 1997-07-09 EP disclosed
US-5504242-A Acyl carbamate containing a hydroxyl group and process for producing the same NIPPON PAINT CO., LTD. (JP) 1996-04-02 US disclosed
WO-1996009297-A1 COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION ARRIS PHARMACEUTICAL CORPORATION (US) 1996-03-28 WO disclosed