Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727311 | 0.90 | KCNH2 (0.39) | MEN1KMT2AKCNH2CHRM2CHRM1 | |
| Bromide SCHEMBL4779649 | 0.89 | KCNH2 (0.38) | MEN1KMT2AKCNH2CHRM2CHRM1 | |
| SCHEMBL14291317 | 0.89 | KCNH2 (0.39) | MEN1KMT2AKCNH2HRH3CHRM2 | |
| SCHEMBL13329547 | 0.87 | MEN1 (0.44) | MEN1KMT2AKCNH2CA12CA1 | |
| Bromide SCHEMBL2871286 | 0.86 | MEN1 (0.43) | MEN1KMT2AKCNH2CA12CA1 | |
| Bromide SCHEMBL2871288 | 0.86 | MEN1 (0.43) | MEN1KMT2AKCNH2CA12CA1 | |
| SCHEMBL4727438 | 0.84 | CHRNA7 (0.38) | MEN1KMT2AKCNH2NPY2RCHRM2 | |
| SCHEMBL4778055 | 0.81 | CHRM2 (0.37) | MEN1KMT2AKCNH2CHRM2CHRM1 | |
| SCHEMBL4782438 | 0.80 | MEN1 (0.38) | MEN1KMT2ANPY2R | |
| SCHEMBL4726502 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AKCNH2TSHRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023157-A1 | NITROGEN CONTAINING HETEROCYCLIC COMPOUNDS USEFUL AS M3-RECEPTOR MODULATORS | ARGENTA DISCOVERY LIMITED (GB) | 2008-02-28 | — | — | WO | disclosed |