Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TK1 | P04183 | 4/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728684 | 0.97 | POLB (0.59) | POLBTK1TYMS | |
| SCHEMBL4725280 | 0.96 | POLB (0.58) | POLBTK1TYMS | |
| SCHEMBL4727506 | 0.94 | POLB (0.62) | POLBTK1TYMS | |
| SCHEMBL5367837 | 0.90 | POLB (0.60) | POLBTK1TYMS | |
| SCHEMBL5163079 | 0.90 | POLB (0.60) | POLBTK1TYMS | |
| SCHEMBL622019 | 0.89 | POLB (0.63) | POLBTK1TYMS | |
| SCHEMBL888318 | 0.88 | POLB (0.65) | POLBTK1TYMS | |
| SCHEMBL1517627 | 0.87 | POLB (0.64) | POLBTK1TYMS | |
| SCHEMBL6829899 | 0.87 | POLB (0.64) | POLBTK1TYMS | |
| SCHEMBL6753328 | 0.87 | POLB (0.61) | POLBTK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024826-A2 | RADIOHALOTHYMIDINES AND METHODS OF THEIR SYNTHESIS AND USE IN PET IMAGING OF CANCERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-02-28 | — | — | WO | disclosed |