Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TK1 | P04183 | 2/20 | 0.60 |
| ▸ | TK2 | O00142 | 1/20 | 0.55 |
| ▸ | TYMS | P04818 | 1/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367837 | 1.00 | POLB (0.60) | POLBTK1TK2TYMSBCHE | |
| SCHEMBL4728684 | 0.91 | POLB (0.59) | POLBTK1TYMS | |
| SCHEMBL4725280 | 0.90 | POLB (0.58) | POLBTK1TYMS | |
| SCHEMBL4727317 | 0.90 | POLB (0.60) | POLBTK1TYMS | |
| Thymidine Monophosphate SCHEMBL9079409 | 0.90 | POLB (0.66) | POLBTK1TYMS | |
| SCHEMBL622019 | 0.89 | POLB (0.63) | POLBTK1TYMS | |
| SCHEMBL16359946 | 0.88 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL887852 | 0.88 | TK1 (0.69) | POLBTK1TYMSBCHE | |
| SCHEMBL4727506 | 0.88 | POLB (0.62) | POLBTK1TYMS | |
| SCHEMBL888318 | 0.88 | POLB (0.65) | POLBTK1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032405-A4 | ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN | WELLSTAT THERAPEUTICS CORP (US) | 2007-05-02 | — | — | EP | claimed |
| US-20020006913-A1 | ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN | PRO-NEURON, INC. | 2002-01-17 | — | — | US | claimed |
| US-20010044421-A1 | Administering to skin a composition containing deoxyribonucleosides in concentrations sufficient to enhance DNA repair or reduce mutation frequency in a vehicle capable of delivering deoxyribonucleosides to skin cells | PRO-NEURON, INC. | 2001-11-22 | — | — | US | claimed |
| US-20010044419-A1 | Antimutagenic compositions for treatment and prevention of photodamage to skin | PRO-NEURON, INC. | 2001-11-22 | — | — | US | claimed |
| EP-1032405-A1 | ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN | PRO-NEURON, INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999022741-A1 | ANTIMUTAGENIC COMPOSITIONS FOR TREATMENT AND PREVENTION OF PHOTODAMAGE TO SKIN | PRO-NEURON, INC. (US) | 1999-05-14 | — | — | WO | claimed |