Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783017 | 0.99 | MAPK14 (0.41) | CNR2CNR1KITMAPK14ABHD6 | |
| SCHEMBL4725924 | 0.96 | MAPK14 (0.43) | CNR2CNR1MAPK14RAF1BRAF | |
| SCHEMBL4730967 | 0.93 | RAF1 (0.44) | MAPK14RAF1BRAF | |
| SCHEMBL4726017 | 0.92 | CCNT1 (0.41) | MAPK14RAF1BRAFRET | |
| SCHEMBL4729211 | 0.91 | MAPK14 (0.40) | MAPK14RAF1BRAFRET | |
| SCHEMBL4728315 | 0.89 | MAPK14 (0.38) | MAPK14RAF1BRAF | |
| SCHEMBL4727823 | 0.87 | MAPK14 (0.45) | MAPK14RAF1BRAF | |
| SCHEMBL4728370 | 0.87 | MAPK14 (0.45) | MAPK14RAF1BRAF | |
| SCHEMBL4727004 | 0.87 | RAF1 (0.43) | MAPK14RAF1BRAF | |
| SCHEMBL4730324 | 0.86 | MAPK14 (0.42) | MAPK14RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |