Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Ethanol SCHEMBL28552574 | 0.84 | LMNA (0.54) | LMNAMAPK1CES1MEN1KMT2A | |
| Diphenylmethanol SCHEMBL4504519 | 0.83 | LMNA (0.48) | LMNAMAPK1CES1CYP2D6SRC | |
| Phenyl Ethanol SCHEMBL29265545 | 0.82 | LMNA (0.52) | LMNAMAPK1CES1MEN1KMT2A | |
| Phenyl Ethanol SCHEMBL28168515 | 0.82 | LMNA (0.52) | LMNAMAPK1CES1MEN1KMT2A | |
| Phenyl Ethanol SCHEMBL1202059 | 0.82 | LMNA (0.52) | LMNAMAPK1CES1MEN1KMT2A | |
| Phenyl Ethanol SCHEMBL27983937 | 0.82 | LMNA (0.52) | LMNAMAPK1MEN1KMT2AADRA2A | |
| Phenyl Ethanol SCHEMBL7144 | 0.82 | — | — | |
| Phenyl Ethanol SCHEMBL2165 | 0.82 | — | — | |
| Phenyl Ethanol SCHEMBL8075664 | 0.82 | LMNA (0.56) | LMNAMAPK1MEN1KMT2AADRA2A | |
| Phenyl Ethanol SCHEMBL2164 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024634-A1 | PYRIMDINE COMPOUNDS USEFUL AS KINASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-28 | — | — | WO | disclosed |
| CN-1859912-A | Inhibitors of Akt activity | SMITHKLINE BEECHAM CORP (US) | 2006-11-08 | — | — | CN | disclosed |