Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 19/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731860 | 0.84 | CCR2 (0.49) | CCR2TACR1KCNH2 | |
| SCHEMBL4731341 | 0.79 | CCR2 (0.56) | CCR2 | |
| SCHEMBL4729722 | 0.79 | CCR2 (0.53) | CCR2TACR1 | |
| SCHEMBL4728693 | 0.77 | CCR2 (0.51) | CCR2TACR1 | |
| SCHEMBL4732209 | 0.77 | CCR2 (0.51) | CCR2TACR1 | |
| SCHEMBL4732759 | 0.72 | CCR2 (0.49) | CCR2 | |
| SCHEMBL4731999 | 0.71 | CCR2 (0.49) | CCR2 | |
| SCHEMBL14513630 | 0.71 | CCR2 (0.81) | CCR2 | |
| SCHEMBL3039259 | 0.71 | CCR2 (0.48) | CCR2KCNH2 | |
| SCHEMBL4733318 | 0.70 | CCR2 (0.44) | CCR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |