Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.72 |
| ▸ | CA2 | P00918 | 2/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA3 | P07451 | 1/20 | 0.72 |
| ▸ | CA4 | P22748 | 1/20 | 0.72 |
| ▸ | CA6 | P23280 | 1/20 | 0.72 |
| ▸ | CA5A | P35218 | 1/20 | 0.72 |
| ▸ | CA7 | P43166 | 1/20 | 0.72 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.72 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.72 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.72 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21731734 | 1.00 | CA1 (0.72) | CA1CA2CA12CA3CA4 | |
| SCHEMBL12240240 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL1697369 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL2742289 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL2606494 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL47275 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL8205298 | 0.86 | CA12 (0.74) | CA1CA2CA12CA3CA4 | |
| SCHEMBL7356728 | 0.85 | CA12 (0.72) | CA1CA2CA12CA3CA4 | |
| SCHEMBL22905316 | 0.84 | CA1 (0.70) | CA1CA2CA12CA3CA4 | |
| Lacosamide SCHEMBL223961 | 0.84 | CA12 (1.00) | CA1CA2CA12CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001710-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2012-01-05 | — | — | WO | disclosed |