Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.74 |
| ▸ | CA1 | P00915 | 1/20 | 0.74 |
| ▸ | CA2 | P00918 | 1/20 | 0.74 |
| ▸ | CA3 | P07451 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | CA6 | P23280 | 1/20 | 0.74 |
| ▸ | CA5A | P35218 | 1/20 | 0.74 |
| ▸ | CA7 | P43166 | 1/20 | 0.74 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.74 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.74 |
| ▸ | CA9 | Q16790 | 1/20 | 0.74 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | MMP8 | P22894 | 3/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.57 |
| ▸ | CTSK | P43235 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205298 | 1.00 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL47275 | 1.00 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL1895974 | 0.88 | CA1 (0.70) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12240240 | 0.88 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2742289 | 0.88 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL2606494 | 0.88 | CA12 (0.74) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12840933 | 0.87 | CA12 (0.62) | CA12CA1CA2CA3CA4 | |
| SCHEMBL20720018 | 0.87 | MMP8 (0.61) | CA12CA1CA2CA3CA4 | |
| SCHEMBL12505312 | 0.87 | MMP8 (0.61) | CA12CA1CA2CA3CA4 | |
| SCHEMBL7356728 | 0.86 | CA12 (0.72) | CA12CA1CA2CA3CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271200-A | Industrial preparation method and application of lacosamide | 北京澳合药物研究院有限公司 | 2024-07-02 | — | — | CN | claimed |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES PRIVATE LIMITED (IN) | 2013-02-14 | — | — | US | claimed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | claimed |
| WO-2011130615-A2 | PREPARATION OF LACOSAMIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-10-20 | — | — | WO | claimed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | claimed |
| CN-118271200-A | Industrial preparation method and application of lacosamide | 北京澳合药物研究院有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-112745242-A | Lacosamide impurity and preparation and application thereof | 浙江华海药业股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| CN-111269140-A | Preparation method of lacosamide | 上海奥博生物医药技术有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-106811492-B | A kind of preparation method of scheme for lacosamide | Changxing Pharmaceutical Co.,Ltd. (CN) | 2019-11-01 | — | — | CN | disclosed |
| EP-3144295-B1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | DIVIS LABORATORIES LTD (IN) | 2018-12-05 | — | — | EP | disclosed |
| EP-3144295-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | Divi's Laboratories Limited (IN) | 2017-03-22 | — | — | EP | disclosed |
| EP-3144295-A1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | Divi's Laboratories Limited (IN) | 2017-03-22 | — | — | EP | disclosed |
| EP-2534127-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN Laboratories Limited (IN) | 2012-12-19 | — | — | EP | disclosed |
| EP-2444390-A1 | Process for producing Lacosamide | Archimica GmbH (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120095251-A1 | Process for Producing Lacosamide | EUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
| WO-2011144983-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF LACOSAMIDE | AUROBINDO PHARMA LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011130615-A2 | PREPARATION OF LACOSAMIDE | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-10-20 | — | — | WO | disclosed |
| WO-2011099033-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | MSN LABORATORIES LIMITED (IN) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011092559-A1 | PROCESS FOR THE SYNTHESIS OF LACOSAMIDE | ARCHIMICA SRL (IT) | 2011-08-04 | — | — | WO | disclosed |
| EP-0996435-B1 | AMINO ACID DERIVATIVES USEFUL TO TREAT STROKE | RES CORP TECHNOLOGIES INC (US) | 2002-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095251-A1 | Process for Producing Lacosamide | NAAA, TET3, GNMT | CA12 168/4885CA1 126/4885CA2 53/4885 |
| US-20130041180-A1 | PROCESS FOR PREPARING (R)-2-ACETAMIDO-N-BENZYL-3-METHOXY-PROPIONAMIDE | AMY1A, PTMA, NAAA | CA12 3088/4885CA1 1930/4885CA2 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.