Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.57 |
| ▸ | HTR2C | P28335 | 17/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726199 | 0.90 | HTR2A (0.68) | HTR2AHTR2C | |
| SCHEMBL4729627 | 0.87 | HTR2A (0.65) | HTR2AHTR2C | |
| SCHEMBL4780050 | 0.84 | HTR2A (0.63) | HTR2AHTR2C | |
| SCHEMBL4726213 | 0.84 | HTR2A (0.54) | HTR2AHTR2C | |
| SCHEMBL4727433 | 0.83 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL4728076 | 0.82 | HTR2A (0.70) | HTR2AHTR2C | |
| SCHEMBL29573693 | 0.82 | HTR2A (0.83) | HTR2AHTR2C | |
| SCHEMBL15248577 | 0.82 | HTR2A (0.67) | HTR2AHTR2C | |
| SCHEMBL5056285 | 0.82 | HTR2A (0.83) | HTR2AHTR2C | |
| SCHEMBL4781004 | 0.81 | HTR2A (0.64) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | claimed |
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |