Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.40 |
| ▸ | BRAF | P15056 | 11/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 4/20 | 0.39 |
| ▸ | MERTK | Q12866 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727070 | 0.90 | RAF1 (0.46) | RAF1BRAFAXLMERTK | |
| SCHEMBL4728221 | 0.84 | HPGD (0.48) | — | |
| SCHEMBL4728365 | 0.83 | RAF1 (0.41) | RAF1BRAF | |
| SCHEMBL4727373 | 0.83 | RAF1 (0.47) | RAF1BRAFAXLMERTKRXFP1 | |
| SCHEMBL4727073 | 0.81 | MAPK14 (0.48) | RAF1BRAFAXLMERTK | |
| SCHEMBL4725917 | 0.81 | RAF1 (0.44) | RAF1BRAF | |
| SCHEMBL4781617 | 0.79 | MAPT (0.46) | RXFP1 | |
| SCHEMBL4847531 | 0.78 | RAF1 (0.47) | RAF1BRAF | |
| SCHEMBL4727417 | 0.76 | STIM1 (0.44) | RAF1BRAFRXFP1 | |
| SCHEMBL4729229 | 0.75 | MEN1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021388-A1 | HETEROARYL DERIVATIVES AS CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-02-21 | — | — | WO | disclosed |