Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5115395 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL3449044 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL5115398 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL22499474 | 0.81 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL5232201 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL18781780 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL15767609 | 0.78 | MEN1 (0.54) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL737656 | 0.78 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL12730443 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MAPTKMT2A | |
| SCHEMBL14540662 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008032027-A1 | PYRIMIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2008-03-20 | — | — | WO | disclosed |