Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.83 |
| ▸ | CASP6 | P55212 | 2/20 | 0.83 |
| ▸ | RAD52 | P43351 | 1/20 | 0.83 |
| ▸ | CASP7 | P55210 | 1/20 | 0.83 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.78 |
| ▸ | HSP90AB1 | P08238 | 10/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | TDP2 | O95551 | 1/20 | 0.66 |
| ▸ | FGB | P02675 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL11546533 | 0.94 | CASP6 (0.94) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| Pyrophosphoric Acid SCHEMBL11546529 | 0.91 | CASP6 (0.86) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL14424689 | 0.84 | NSD2 (0.93) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL14424701 | 0.84 | NSD2 (0.93) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL4726902 | 0.84 | NSD2 (0.70) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL8902067 | 0.84 | NSD2 (0.70) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| Hydrochloric Acid SCHEMBL11541621 | 0.83 | NSD2 (0.69) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL10731810 | 0.82 | NSD2 (0.71) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL10731681 | 0.82 | NSD2 (0.71) | NSD2CASP6RAD52CASP7HSP90AA1 | |
| SCHEMBL4729971 | 0.82 | NSD2 (0.71) | NSD2CASP6RAD52CASP7HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021210-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | COMBINATORX, INCORPORATED (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | CHDI, INCORPORATED | 2008-02-21 | — | — | US | disclosed |
| US-4167638-A | Process for production of 8-NHR quinolines | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1979-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044390-A1 | Methods and compositions for the treatment of neurodegenerative disorders | HTT, SNCA, NLN | NSD2 1540/4885CASP6 897/4885RAD52 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.