SCHEMBL4728539

SCHEMBL4728539

CCC(Oc1ccc(CCC=NOCc2nc(C(C)(C)C)oc2C)cc1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 18/20 0.39
PPARG P37231 17/20 0.39
PPARD Q03181 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
FFAR1 O14842 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728540 0.85 PPARG (0.56) PPARAPPARGPPARDFFAR1
SCHEMBL4728610 0.84 PPARA (0.49) PPARAPPARGPPARDFFAR1
SCHEMBL4729706 0.84 PPARG (0.45) PPARAPPARGPPARDSMN1; SMN2FFAR1
SCHEMBL4726243 0.81 PPARA (0.38) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4729792 0.79 SMN1; SMN2 (0.43) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4728537 0.79 SMN1; SMN2 (0.43) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4730221 0.77 PPARG (0.47) PPARAPPARGSMN1; SMN2FFAR1
SCHEMBL4726779 0.76 PPARG (0.48) PPARAPPARGSMN1; SMN2FFAR1
SCHEMBL4728887 0.75 PPARG (0.46) PPARAPPARGSMN1; SMN2
SCHEMBL4727918 0.73 PPARG (0.46) PPARAPPARGSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO claimed
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed