SCHEMBL4726243

SCHEMBL4726243

CCC(Oc1ccc(CC=NOCc2nc(C(C)(C)C)oc2C)cc1C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.38
PPARG P37231 14/20 0.37
PPARD Q03181 5/20 0.36
SMN1; SMN2 Q16637 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4730644 0.86 PPARG (0.53) PPARAPPARGPPARD
SCHEMBL4731241 0.85 PPARG (0.49) PPARAPPARGPPARD
SCHEMBL4729101 0.84 PPARD (0.47) PPARAPPARGPPARD
SCHEMBL4728539 0.81 PPARA (0.39) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4726239 0.81 PPARA (0.52) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4729317 0.81 PPARA (0.52) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4728593 0.78 PPARA (0.48) PPARAPPARGPPARDSMN1; SMN2PTGDR2
SCHEMBL4729759 0.77 PPARA (0.41) PPARAPPARGPPARDSMN1; SMN2
SCHEMBL4726349 0.76 PPARG (0.48) PPARAPPARGPPARD
SCHEMBL4728557 0.76 CDK8 (0.36) PPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008035359-A2 OXIMINOPHENOXYALKANOIC ACID AND PHENYLALKANOIC ACID DERIVATIVES CADILA HEALTHCARE LIMITED (IN) 2008-03-27 WO disclosed