Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14177426 | 1.00 | GRIK1 (0.58) | GRIK1SLC1A3SLC1A2SLC1A1HDAC3 | |
| SCHEMBL14169359 | 1.00 | GRIK1 (0.58) | GRIK1SLC1A3SLC1A2SLC1A1HDAC3 | |
| SCHEMBL14169646 | 0.95 | GRIK1 (0.53) | GRIK1SLC1A3SLC1A2SLC1A1HDAC3 | |
| SCHEMBL14169346 | 0.90 | GRIK1 (0.55) | GRIK1SLC1A3SLC1A2SLC1A1HDAC3 | |
| SCHEMBL1881095 | 0.89 | SLC1A3 (0.53) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL10654495 | 0.89 | SLC1A3 (0.53) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL1880545 | 0.89 | SLC1A3 (0.53) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL1884112 | 0.89 | SLC1A3 (0.53) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1886816 | 0.88 | SLC1A3 (0.51) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 | |
| Hydrochloric Acid SCHEMBL1881444 | 0.88 | SLC1A3 (0.51) | GRIK1SLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139455-A1 | COMPOUNDS AND METHODS OF TREATING METABOLIC SYNDROME AND INFLAMMATION | FORBES MEDI-TECH (RESEARCH), INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20080139455-A1 | COMPOUNDS AND METHODS OF TREATING METABOLIC SYNDROME AND INFLAMMATION | FORBES MEDI-TECH (RESEARCH), INC. (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2008046071-A2 | COMPOUNDS AND METHODS OF TREATING METABOLIC SYNDROME AND INFLAMMATION | TRANSITION THERAPEUTICS INC. (CA) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139455-A1 | COMPOUNDS AND METHODS OF TREATING METABOLIC SYNDROME AND INFLAMMATION | PNLIP, CPT1A, CPT1B | GRIK1 2116/4885SLC1A3 4647/4885SLC1A2 4801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.