Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RORC | P51449 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865717 | 0.87 | PTGER4 (0.65) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL27839200 | 0.86 | KDM4E (0.58) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL10579016 | 0.85 | KDM4E (0.67) | KDM4ELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL27609720 | 0.84 | KDM4E (0.55) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL5662028 | 0.84 | HPGD (0.72) | KDM4ELMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL30150496 | 0.84 | KDM4E (0.68) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL7979578 | 0.84 | KDM4E (0.68) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL2734561 | 0.84 | ALDH1A1 (0.78) | PTGER4KDM4ELMNAMAPTNPSR1 | |
| SCHEMBL17938355 | 0.83 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL4727906 | 0.83 | PTGER4 (0.67) | PTGER4KDM4ELMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |