Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.57 |
| ▸ | HTR1D | P28221 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR1E | P28566 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18309830 | 0.88 | KMT2A (0.79) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL4725750 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL7030069 | 0.84 | HTR1B (0.80) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL6950544 | 0.84 | KMT2A (0.72) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL14041628 | 0.82 | KMT2A (0.70) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL2016322 | 0.81 | KMT2A (0.68) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL2016008 | 0.79 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL11576749 | 0.79 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL4728400 | 0.79 | KMT2A (0.65) | KMT2AMEN1ALDH1A1LMNARAB9A | |
| SCHEMBL23657201 | 0.78 | KMT2A (0.64) | KMT2AMEN1ALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2006012310-A2 | CARBAZOLE DERIVATIVES FOR TREATING POLYCYSTIC KIDNEY DISEASE | GENZYME CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |