Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTR1B | P28222 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | HTR1E | P28566 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726479 | 0.91 | KMT2A (0.67) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL4727890 | 0.86 | KDM4E (0.56) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL22134580 | 0.86 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL5808503 | 0.86 | KMT2A (0.61) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL20601994 | 0.86 | SIRT1 (0.58) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL4895642 | 0.86 | KMT2A (0.51) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL541423 | 0.85 | HTR1D (0.60) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL7973723 | 0.84 | KMT2A (0.58) | KMT2AMEN1NPC1RAB9AHTR1B | |
| SCHEMBL4727252 | 0.83 | KDM4E (0.64) | KMT2AMEN1MAPTGAAHSD17B10 | |
| SCHEMBL31078247 | 0.83 | KDM4E (0.64) | KMT2AMEN1MAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |