Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 6/20 | 0.61 |
| ▸ | PTGDR2 | Q9Y5Y4 | 10/20 | 0.52 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728754 | 0.97 | SCARB1 (0.60) | SCARB1PTGDR2RORCRXFP1 | |
| SCHEMBL4188561 | 0.85 | SCARB1 (0.67) | SCARB1PTGDR2RORC | |
| SCHEMBL4025480 | 0.84 | SCARB1 (0.61) | SCARB1PTGDR2RORC | |
| SCHEMBL4030252 | 0.83 | SCARB1 (0.70) | SCARB1PTGDR2RORC | |
| SCHEMBL4189175 | 0.82 | SCARB1 (0.69) | SCARB1PTGDR2RORC | |
| SCHEMBL4024931 | 0.82 | SCARB1 (0.69) | SCARB1PTGDR2RORC | |
| SCHEMBL4028758 | 0.82 | SCARB1 (0.72) | SCARB1PTGDR2RORC | |
| SCHEMBL4029504 | 0.81 | SCARB1 (0.68) | SCARB1PTGDR2RORC | |
| SCHEMBL4195549 | 0.81 | SCARB1 (0.68) | SCARB1PTGDR2RORC | |
| SCHEMBL4024404 | 0.81 | SCARB1 (0.58) | SCARB1PTGDR2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |