Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734561 | 0.86 | ALDH1A1 (0.78) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| Formaldehyde SCHEMBL27586290 | 0.84 | ALDH1A1 (0.74) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL15775024 | 0.81 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL13011314 | 0.80 | PTGER4 (0.59) | PTGER4ALDH1A1HPGDNPY5RCNR2 | |
| SCHEMBL8922345 | 0.79 | HPGD (0.65) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29629312 | 0.79 | HPGD (0.65) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL29629313 | 0.79 | HPGD (0.65) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL27722947 | 0.78 | ALDH1A1 (0.65) | PTGER4ALDH1A1HPGDKDM4EMEN1 | |
| Benzoic Acid SCHEMBL11711283 | 0.78 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8920877 | 0.78 | HPGD (0.63) | PTGER4ALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |