Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.55 |
| ▸ | TSPO | P30536 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828645 | 0.87 | CNR2 (0.60) | CNR2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL600862 | 0.86 | CNR2 (1.00) | CNR2ALDH1A1HPGD | |
| SCHEMBL4778681 | 0.84 | CNR2 (0.56) | CNR2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL10579016 | 0.84 | KDM4E (0.67) | CNR2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL2734561 | 0.82 | ALDH1A1 (0.78) | CNR2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL5662028 | 0.82 | HPGD (0.72) | KDM4EMAPTLMNAALDH1A1HPGD | |
| SCHEMBL7979578 | 0.82 | KDM4E (0.68) | KDM4EMAPTLMNAALDH1A1HPGD | |
| SCHEMBL30150496 | 0.82 | KDM4E (0.68) | KDM4EMAPTLMNAALDH1A1HPGD | |
| SCHEMBL11805763 | 0.82 | CNR2 (0.53) | CNR2KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL2600220 | 0.81 | KDM4E (0.63) | CNR2KDM4EMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021745-A2 | HEPATITIS C VIRUS ENTRY INHIBITORS | ITHERX PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |