Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001725 | 0.84 | TACR1 (0.39) | TACR1SLC6A4 | |
| SCHEMBL3995308 | 0.82 | PIM1 (0.35) | TACR1PIM1 | |
| SCHEMBL3996741 | 0.80 | PARP1 (0.41) | DRD4DRD2 | |
| SCHEMBL3997786 | 0.79 | KCNH2 (0.34) | TACR1SLC6A4PIM1 | |
| SCHEMBL3996200 | 0.79 | TACR1 (0.36) | TACR1SLC6A4 | |
| SCHEMBL4000751 | 0.78 | TACR1 (0.36) | TACR1DRD2 | |
| SCHEMBL3997549 | 0.78 | PIM1 (0.34) | TACR1PIM1 | |
| SCHEMBL4003970 | 0.77 | TACR1 (0.36) | TACR1SLC6A4 | |
| SCHEMBL4730021 | 0.77 | TACR1 (0.38) | TACR1SLC6A4 | |
| SCHEMBL4732027 | 0.77 | TACR1 (0.38) | TACR1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | disclosed |