Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 9/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 8/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12820476 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL4580373 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL3632100 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL4581365 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL12820379 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL14252159 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL3632098 | 0.84 | PRKCQ (0.48) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL3626121 | 0.81 | PRKCQ (0.46) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL8145441 | 0.81 | PRKCQ (0.46) | PRKCQPRKCDCHUKMEN1KMT2A | |
| SCHEMBL4725141 | 0.80 | PRKCQ (0.52) | PRKCQPRKCDCHUKKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008024970-A2 | TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |