Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 6/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.39 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074639 | 0.91 | KMT2A (0.47) | PRKCQKMT2AKDM4EGAATSHR | |
| SCHEMBL2666741 | 0.84 | KDM4E (0.53) | KMT2AKDM4EGAATSHRHPGD | |
| SCHEMBL7526224 | 0.84 | KMT2A (0.51) | KMT2AKDM4EGAATSHRHPGD | |
| SCHEMBL5241822 | 0.83 | PRKCQ (0.45) | PRKCQPRKCDKMT2ACHUKKDM4E | |
| SCHEMBL3476117 | 0.83 | KDM4E (0.56) | KMT2AKDM4EGAATSHRHPGD | |
| SCHEMBL4878796 | 0.81 | AR (0.50) | PRKCQPRKCDCHUKAR | |
| SCHEMBL4878791 | 0.81 | AR (0.50) | PRKCQPRKCDCHUKAR | |
| SCHEMBL4726704 | 0.80 | KMT2A (0.45) | PRKCQPRKCDKMT2AKDM4EGAA | |
| SCHEMBL377808 | 0.80 | CTSL (0.42) | KMT2AKDM4EGAATSHRHPGD | |
| SCHEMBL4728979 | 0.80 | PRKCQ (0.49) | PRKCQPRKCDKMT2ACHUKL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047781-A | HSP90 inhibitor and preparation method and application thereof | 广西大学 | 2024-05-17 | — | — | CN | disclosed |
| WO-2008024970-A2 | TETRAHYDROINDOLONE AND TETRAHYDROINDAZOLONE DERIVATIVES | SERENEX, INC. (US) | 2008-02-28 | — | — | WO | disclosed |