Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.69 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | MASP2 | O00187 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 8/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142763 | 0.83 | HCAR2 (0.74) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL979497 | 0.83 | HCAR2 (0.74) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL979495 | 0.83 | HCAR2 (0.74) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL11045884 | 0.82 | HCAR2 (0.71) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL2561722 | 0.82 | HCAR2 (1.00) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL8763706 | 0.82 | HCAR2 (0.71) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL125126 | 0.82 | HCAR2 (1.00) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL125125 | 0.82 | HCAR2 (1.00) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL5307638 | 0.80 | HCAR2 (0.69) | HCAR2MAOAMAOBMASP2F2 | |
| SCHEMBL16198044 | 0.80 | HCAR2 (0.69) | HCAR2MAOAMAOBMASP2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008011074-A2 | HISTONE DEACETYLASE INHIBITORS | ERRANT GENE THERAPEUTICS, LLC (US) | 2008-01-24 | — | — | WO | disclosed |