SCHEMBL979495

SCHEMBL979495

O=C(/C=C/c1ccco1)/C=C/c1ccco1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.74
POLB P06746 7/20 0.65
MAPT P10636 6/20 0.65
KMT2A Q03164 5/20 0.65
MEN1 O00255 4/20 0.65
RAB9A P51151 4/20 0.65
L3MBTL1 Q9Y468 4/20 0.65
TDP1 Q9NUW8 4/20 0.65
NPC1 O15118 3/20 0.65
BLM P54132 2/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
CYP1A2 P05177 1/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2D6 P10635 1/20 0.65
NFKB1 P19838 1/20 0.65
CYP2C19 P33261 1/20 0.65
NFKB2 Q00653 1/20 0.65
RELA Q04206 1/20 0.65
CTDSP1 Q9GZU7 1/20 0.65
MASP2 O00187 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL979497 1.00 HCAR2 (0.74) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL7142763 1.00 HCAR2 (0.74) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL28993560 0.88 HCAR2 (0.65) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL28360825 0.86 KMT2A (0.68) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL11701260 0.86 MASP2 (0.77) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL11701268 0.86 MASP2 (0.77) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL11653185 0.85 HCAR2 (0.61) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL11653187 0.85 HCAR2 (0.61) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL2561722 0.85 HCAR2 (1.00) HCAR2POLBMAPTKMT2AMEN1
SCHEMBL125125 0.85 HCAR2 (1.00) HCAR2POLBMAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122047026-A Constant/unsteady hydrodynamic performance simulation method based on propeller modeling of ship propeller shaft system 上海交通大学 2026-05-15 CN claimed
CN-121582676-A Deep learning-based power transmission corridor overhead line fastener corrosion detection method 广东工业大学 2026-02-27 CN claimed
CN-119760502-A Automatic driving road side collaborative sensing method based on variability implicit feature alignment 长沙理工大学 2025-04-04 CN claimed
CN-117243587-B Sleep time extraction method for household health monitoring radar 北京理工雷科电子信息技术有限公司 2025-02-28 CN claimed
CN-118608359-A Method for identifying and predicting key influence factors of departure flight sliding time 中国电子科技集团公司第二十八研究所 2024-09-06 CN claimed
CN-117243587-A Sleep time extraction method for household health monitoring radar 北京理工雷科电子信息技术有限公司 2023-12-19 CN claimed
CN-115197891-B Extraction method of exosomes 广州惠善医疗技术有限公司 2023-07-25 CN claimed
EP-4162150-A1 AUTOMATED ELECTRIC SUBMERSIBLE PUMP (ESP) FAILURE ANALYSIS Services Pétroliers Schlumberger (FR) 2023-04-12 EP claimed
CN-115448907-A Compound for treating peptic ulcer, intermediate and preparation method 赛隆药业集团股份有限公司 2022-12-09 CN claimed
CN-115197891-A Method for extracting exosome 广州惠善医疗技术有限公司 2022-10-18 CN claimed
CN-114459052-B Coal-fired boiler NOx emission optimization method and device based on improved SSA 东北电力大学 2022-09-09 CN claimed
CN-114464266-B Pulverized coal boiler NOx emission prediction method and device based on improved SSA-GPR 东北电力大学 2022-08-02 CN claimed
CN-109613435-B Method and system for detecting voltage acquisition abnormity caused by non-self fault of battery 常州普莱德新能源电池科技有限公司 2022-07-05 CN claimed
WO-2026099756-A1 PRESSURE MANAGEMENT UNIT OF THE ANNULUS OF AN OIL WELL AND CONTROL METHOD FOR PRESSURE REGULATION SINERGIA S.P.A. (IT) 2026-05-15 WO disclosed
CN-122047026-A Constant/unsteady hydrodynamic performance simulation method based on propeller modeling of ship propeller shaft system 上海交通大学 2026-05-15 CN disclosed
CN-120536605-B Primer system for rapidly detecting pinellia ternate bacterial pathogens and detection method and application thereof 湖北省农业科学院中药材研究所 2026-03-20 CN disclosed
US-6906105-B2 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states BOWEN J PHILLIP (US) 2005-06-14 US disclosed
US-20030027830-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2003-02-06 US disclosed
US-6462075-B1 USE OF CHALCONE AND ITS DERIVATIVES AS ANTITUMOR/ANTICANCER AGENTS AND TO TREAT A NUMBER OF CONDITIONS OR DISEASE STATES IN WHICH ANGIOGENESIS IS A FACTOR INCLUDING PSORIASIS, ACNE, ROSACEA, WARTS, ECZEMA, HEMANGIOMAS AND LYMPHANGIOGENESIS THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2002-10-08 US disclosed
US-20020040029-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states BOWEN, J. PHILLIP 2002-04-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040029-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, FLT4, VEGFA HCAR2 201/4885POLB 2779/4885MAPT 1111/4885
US-20030027830-A1 Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states FLT1, VEGFA, FLT4 HCAR2 334/4885POLB 1937/4885MAPT 341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.