⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aziridine SCHEMBL4732220 | 0.95 | CRBN (0.43) | — | |
| SCHEMBL11308019 | 0.83 | — | — | |
| SCHEMBL21635931 | 0.79 | — | — | |
| SCHEMBL22216329 | 0.74 | CRBN (0.35) | — | |
| SCHEMBL116223 | 0.69 | — | — | |
| Methane SCHEMBL10972248 | 0.67 | — | — | |
| Charcoal, Activated SCHEMBL30614618 | 0.67 | — | — | |
| SCHEMBL7476994 | 0.66 | — | — | |
| SCHEMBL42430 | 0.66 | — | — | |
| SCHEMBL9058472 | 0.66 | CRBN (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045998-A3 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRIDINE COMPOSITIONS | UNIV ARIZONA (US) | 2008-09-18 | — | — | WO | disclosed |
| WO-2008045686-A3 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRDINE COMPOSITIONS | UNIV ARIZONA (US) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008045998-A2 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRIDINE COMPOSITIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008045686-A2 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRDINE COMPOSITIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008045686-A2 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRDINE COMPOSITIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008045998-A2 | ENANTIOMERICALLY ENRICHED IMINOPYRROLIDONE AZIRIDINE COMPOSITIONS | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2008-04-17 | — | — | WO | disclosed |