Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.38 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL472934 | 1.00 | FOLH1 (0.50) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| SCHEMBL472935 | 1.00 | FOLH1 (0.50) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| SCHEMBL1054672 | 0.93 | FOLH1 (0.58) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| SCHEMBL48407 | 0.93 | FOLH1 (0.58) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| SCHEMBL48406 | 0.93 | FOLH1 (0.58) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| Ammonia Solution, Strong SCHEMBL6151757 | 0.91 | FOLH1 (0.56) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| Hydrochloric Acid SCHEMBL4067567 | 0.91 | FOLH1 (0.56) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| Hydrochloric Acid SCHEMBL16732003 | 0.91 | FOLH1 (0.56) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| Methane SCHEMBL28201404 | 0.91 | FOLH1 (0.56) | FOLH1CPB2GSRRNPEPSLC6A5 | |
| Hydrochloric Acid SCHEMBL4067569 | 0.91 | FOLH1 (0.56) | FOLH1CPB2GSRRNPEPSLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265130-B1 | ANTIBACTERIAL SIDEROMYCINS | HSIRI THERAPEUTICS LLC (US) | 2024-05-22 | — | — | EP | disclosed |
| US-11779634-B2 | Fungal iron acquisition inhibitors and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220211820-A1 | FUNGAL IRON ACQUISITION INHIBITORS AND USES THEREOF | UNIV CASE WESTERN RESERVE (US) | 2022-07-07 | — | — | US | disclosed |
| US-11229685-B2 | Fungal iron acquisition inhibitors and uses thereof | CASE WESTERN RESERVE UNIVERSITY (US) | 2022-01-25 | — | — | US | disclosed |
| US-10548860-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190192452-A1 | HIF-1 MODULATOR PAINT FORMULATION AND USES THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2019-06-27 | — | — | US | disclosed |
| US-10220009-B2 | HIF-1 modulator paint formulation and uses thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-03-05 | — | — | US | disclosed |
| EP-2970150-B1 | FORMATION OF N-PROTECTED BIS-3,6-(4-AMINOBUTYL)-2,5-DIKETOPIPERAZINE THROUGH A CYCLIC ALPHA-N-PROTECTED AMINO ESTER | MANNKIND CORP (US) | 2018-09-19 | — | — | EP | disclosed |
| US-9763899-B2 | Iron chelators and use thereof for reducing transplant failure during rejection episodes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170252310-A9 | Iron Chelators and Use Thereof for Reducing Transplant Failure During Rejection Episodes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-09-07 | — | — | US | disclosed |
| WO-1999022593-A1 | USE OF EXOCHELINS IN THE PRESERVATION OF ORGANS FOR TRANSPLANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-05-14 | — | — | WO | disclosed |
| WO-1998058635-A2 | METHOD FOR THE TREATMENT OF CANCER WITH EXOCHELINS OF MYCOBACTERIUM TUBERCULOSIS | KEYSTONE BIOMEDICAL INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| WO-1998034619-A1 | METHOD FOR THE TREATMENT OF ATHEROSCLEROSIS AND VASCULAR INJURY BY PREVENTION OF VASCULAR SMOOTH MUSCLE CELL PROLIFERATION | KEYSTONE BIOMEDICAL, INC. (US) | 1998-08-13 | — | — | WO | disclosed |
| CN-1145588-A | Novel iron chelator and inhibitor of iron-mediated oxidation | UNIV CALIFORNIA (US) | 1997-03-19 | — | — | CN | disclosed |
| EP-0754044-A1 | NOVEL IRON CHELATOR AND INHIBITOR OF IRON-MEDIATED OXIDATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-01-22 | — | — | EP | disclosed |
| WO-1996023502-A1 | NOVEL IRON CHELATOR AS INHIBITOR OF IRON-MEDIATED OXIDATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-08-08 | — | — | WO | disclosed |
| US-4766110-A | INHIBITS ANGIOTENSIN CONVERTING ENZYME, HYPOTENSIVE AGENTS | RYAN JAMES W (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0073143-B1 | NOVEL COMPLEX AMIDO AND IMIDO DERIVATIVES OF CARBOXYALKYL PEPTIDES AND THIOETHERS AND ETHERS OF PEPTIDES | Ryan, James Walter (US) | 1985-11-21 | — | — | EP | disclosed |
| EP-0073143-A2 | Novel complex amido and imido derivatives of carboxyalkyl peptides and thioethers and ethers of peptides | Ryan, James Walter (US) | 1983-03-02 | — | — | EP | disclosed |
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11229685-B2 | Fungal iron acquisition inhibitors and uses thereof | SLC40A1, SLC30A6, SLC30A7 | FOLH1 190/4885CPB2 1262/4885GSR 578/4885 |
| US-20220211820-A1 | FUNGAL IRON ACQUISITION INHIBITORS AND USES THEREOF | SLC40A1, SLC30A6, SLC30A7 | FOLH1 190/4885CPB2 1262/4885GSR 578/4885 |
| US-11779634-B2 | Fungal iron acquisition inhibitors and uses thereof | SLC40A1, SLC30A6, SLC30A7 | FOLH1 190/4885CPB2 1262/4885GSR 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.