Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.79 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055186 | 0.89 | SLC6A4 (1.00) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| Propiolic Acid SCHEMBL143598 | 0.84 | SLC6A4 (0.53) | SLC6A4CYP2D6SLC6A2SLC6A3KCNK2 | |
| SCHEMBL4729431 | 0.79 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3KCNK2KCNH2 | |
| SCHEMBL8197696 | 0.79 | SLC6A4 (1.00) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL5011928 | 0.79 | SLC6A4 (1.00) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| Oxalic Acid SCHEMBL16347641 | 0.79 | SLC6A4 (0.71) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL32660765 | 0.78 | SLC6A4 (0.69) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL18744741 | 0.78 | SLC6A4 (0.69) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL32660758 | 0.78 | SLC6A4 (0.69) | SLC6A4MEN1KMT2ACYP2D6LMNA | |
| SCHEMBL32660760 | 0.78 | SLC6A4 (0.69) | SLC6A4MEN1KMT2ACYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |