Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.54 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730841 | 0.91 | CNR2 (0.53) | CNR2CNR1LMNAMAPTGSK3B | |
| SCHEMBL4733425 | 0.87 | CNR2 (0.67) | CNR2CNR1GSK3BDYRK1APDCD1 | |
| SCHEMBL4732019 | 0.85 | CNR2 (0.70) | CNR2CNR1GSK3BDYRK1APDCD1 | |
| SCHEMBL4729957 | 0.84 | CNR2 (0.60) | CNR2CNR1LMNAMAPTTSHR | |
| SCHEMBL4732125 | 0.83 | CNR2 (0.76) | CNR2CNR1LMNAMAPTTSHR | |
| SCHEMBL4733802 | 0.83 | CNR2 (0.76) | CNR2CNR1LMNAMAPTTSHR | |
| SCHEMBL4734332 | 0.82 | CNR2 (0.63) | CNR2CNR1LMNAMAPTTSHR | |
| SCHEMBL4733039 | 0.82 | CNR2 (0.77) | CNR2CNR1LMNAMAPTTSHR | |
| SCHEMBL4735443 | 0.82 | CNR2 (0.60) | CNR2CNR1LMNAMAPT | |
| SCHEMBL4729643 | 0.82 | CNR2 (0.77) | CNR2CNR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| WO-2008063625-A2 | PYRIDINE COMPOUNDS AND METHODS OF THEIR USE | ADOLOR CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |